FCGR1A Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P12314 |
Other Accession | NM_000566, NP_000557 |
Reactivity | Human, Yeast |
Predicted | Human, Yeast |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 43kDa |
Gene ID | 2209 |
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Alias Symbol | CD64, CD64A, FCRI, FLJ18345, IGFR1 |
Other Names | High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64, FCGR1A, FCG1, FCGR1, IGFR1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-FCGR1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | FCGR1A Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FCGR1A |
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Synonyms | FCG1, FCGR1, IGFR1 |
Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
Cellular Location | Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G |
Tissue Location | Monocyte/macrophage specific. |
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Provided below are standard protocols that you may find useful for product applications.
References
Allen J.M.,et al.Nucleic Acids Res. 16:11824-11824(1988).
Allen J.M.,et al.Science 243:378-381(1989).
Porges A.J.,et al.J. Clin. Invest. 90:2102-2109(1992).
Benech P.D.,et al.J. Exp. Med. 176:1115-1123(1992).
Gregory S.G.,et al.Nature 441:315-321(2006).
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