STOM antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF |
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Primary Accession | P27105 |
Other Accession | NM_004099, NP_004090 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 32kDa |
Gene ID | 2040 |
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Alias Symbol | BND7, EPB7, EPB72 |
Other Names | Erythrocyte band 7 integral membrane protein, Protein 7.2b, Stomatin, STOM, BND7, EPB72 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-STOM antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | STOM antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STOM (HGNC:3383) |
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Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190) Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). |
Tissue Location | Detected in erythrocytes (at protein level). Widely expressed. |
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Provided below are standard protocols that you may find useful for product applications.
References
Hiebl-Dirschmied C.M.,et al.Biochim. Biophys. Acta 1090:123-124(1991).
Stewart G.W.,et al.Blood 79:1593-1601(1992).
Unfried I.,et al.Genomics 30:521-528(1995).
Gallagher P.G.,et al.J. Biol. Chem. 270:26358-26363(1995).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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