Pde2a antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q01062 |
Other Accession | NM_001143847, NP_001137319 |
Reactivity | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 104kDa |
Gene ID | 81743 |
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Alias Symbol | Pde2, Pde2a2, Pde2a |
Other Names | cGMP-dependent 3', 5'-cyclic phosphodiesterase, 3.1.4.17, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE, Pde2a |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Pde2a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Pde2a antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Pde2a {ECO:0000312|RGD:620965} |
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Function | cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP (By similarity). Plays a role in cell growth and migration (By similarity). |
Cellular Location | [Isoform PDE2A3]: Cell membrane {ECO:0000250|UniProtKB:O00408}; Peripheral membrane protein [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane |
Tissue Location | Expressed in brain and liver. |
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Provided below are standard protocols that you may find useful for product applications.
References
Yang Q.,et al.Biochem. Biophys. Res. Commun. 205:1850-1858(1994).
Repaske D.R.,et al.J. Biol. Chem. 267:18683-18688(1992).
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