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Fbxo32 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9CPU7 |
| Other Accession | NM_026346, NP_080622 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Chicken, Horse, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39kDa |
| Gene ID | 67731 |
|---|---|
| Alias Symbol | 4833442G10Rik, AI430017, ATROGIN1, MAFbx, atrogin-1, Gm20361 |
| Other Names | F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, Fbxo32 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Fbxo32 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Fbxo32 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Fbxo32 |
|---|---|
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q969P5}. Nucleus {ECO:0000250|UniProtKB:Q969P5}. Note=Shuttles between cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q969P5} |
| Tissue Location | Specifically expressed in cardiac and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
References
Gomes M.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:14440-14445(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
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