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Acsl4 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9QUJ7 |
| Other Accession | NM_207625, NP_997508 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 79kDa |
| Gene ID | 50790 |
|---|---|
| Alias Symbol | 9430020A05Rik, ACS4, AU018108, Facl4, Lacs4 |
| Other Names | Long-chain-fatty-acid--CoA ligase 4, 6.2.1.3, Long-chain acyl-CoA synthetase 4, LACS 4, mACS4, Acsl4, Acs4, Facl4 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Acsl4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Acsl4 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Acsl4 |
|---|---|
| Synonyms | Acs4, Facl4 |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (By similarity). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60488}; Single-pass type III membrane protein. Cell membrane {ECO:0000250|UniProtKB:O60488} |
| Tissue Location | Abundant in steroidogenic tissues, also found in the kidney, brain and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Cho Y.-Y.,et al.Biochem. Biophys. Res. Commun. 274:741-745(2000).
Vitelli F.,et al.Cytogenet. Cell Genet. 88:259-263(2000).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
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