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SLC30A8 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - SLC30A8 antibody - middle region AI12876

    WB Suggested Anti-SLC30A8 Antibody Titration: 0.2-1 μg/ml
    Positive Control: NCI-H226 cell lysate
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8IWU4
Other Accession NM_173851, NP_776250
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Rabbit, Pig, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Additional Information
Gene ID 169026
Alias Symbol ZnT-8, ZNT8
Other Names Zinc transporter 8, ZnT-8, Solute carrier family 30 member 8, SLC30A8, ZNT8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SLC30A8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSLC30A8 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC30A8 (HGNC:20303)
Function Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion.
Cellular Location Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Associated with insulin and glucagon secretory granules.
Tissue Location In the endocrine pancreas, expressed in insulin- producing beta cells. Expressed at relatively high levels in subcutaneous fat tissue from lean persons; much lower levels in visceral fat, whether from lean or obese individuals, and in subcutaneous fat tissue from obese individuals. Expressed in peripheral blood mononuclear cells, including T-cells and B-cells, with great variation among individuals ranging from negative to strongly positive
Research Areas
Citations (0)
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$ 389.00
Cat# AI12876
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