NSDHL antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q15738 |
Other Accession | NM_015922, NP_057006 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42kDa |
Gene ID | 50814 |
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Alias Symbol | H105E3, XAP104, SDR31E1 |
Other Names | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating, 1.1.1.170, Protein H105e3, NSDHL, H105E3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-NSDHL antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | NSDHL antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NSDHL |
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Synonyms | H105E3 |
Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Also plays a role in the regulation of the endocytic trafficking of EGFR (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet {ECO:0000250|UniProtKB:Q9R1J0} Note=Trafficking through the Golgi is necessary for ER membrane localization. {ECO:0000250|UniProtKB:Q9R1J0} |
Tissue Location | Brain, heart, liver, lung, kidney, skin and placenta |
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Provided below are standard protocols that you may find useful for product applications.
References
Guggenberger,C.,J.SteroidBiochem.Mol.Biol.104(3-5),105-109(2007)ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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