OSMR antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q99650 |
Other Accession | NM_003999, NP_003990 |
Reactivity | Human, Rabbit, Horse, Guinea Pig, Dog |
Predicted | Human, Rabbit, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 110kDa |
Gene ID | 9180 |
---|---|
Alias Symbol | MGC150626, MGC150627, MGC75127, OSMRB, PLCA1 |
Other Names | Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, OSMR, OSMRB |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-OSMR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | OSMR antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OSMR |
---|---|
Synonyms | OSMRB |
Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in keratinocytes (at protein level) (PubMed:21261663). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells (PubMed:8999038) |
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Provided below are standard protocols that you may find useful for product applications.
References
Arita,K.,(2008)Am.J.Hum.Genet.82(1),73-80ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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