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GALC antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - GALC antibody - middle region AI12506

    WB Suggested Anti-GALC Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P54803
Other Accession NM_000153, NP_000144
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 73kDa
Additional Information
Gene ID 2581
Other Names Galactocerebrosidase, GALCERase, 3.2.1.46, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase, GALC
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GALC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGALC antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GALC (HGNC:4115)
Function Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine (PubMed:8281145, PubMed:8399327). Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (PubMed:8281145, PubMed:8399327).
Cellular Location Lysosome.
Tissue Location Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver
Research Areas
Citations (0)
citation

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References

Formichi,P.,(2007)J.Cell.Physiol.212(3),737-743ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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$ 389.00
Cat# AI12506
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