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KIAA1754L antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q6GPH6 |
| Other Accession | NM_001008949, NP_001008949 |
| Reactivity | Human, Rat, Bovine, Dog |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 61kDa |
| Gene ID | 150771 |
|---|---|
| Alias Symbol | KIAA1754L |
| Other Names | Inositol 1, 4, 5-trisphosphate receptor-interacting protein-like 1, ITPRIPL1, KIAA1754L |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-KIAA1754L antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | KIAA1754L antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ITPRIPL1 (HGNC:29371) |
|---|---|
| Synonyms | KIAA1754L |
| Function | Functions as a ligand of CD3E, inhibiting TCR-CD3 complex signaling to regulate T cell activation. Induces stable CD3E-NCK1 binding, thereby preventing the CD3E-ZAP70 interaction and subsequently inhibiting the activation of the downstream ERK-NFkB signaling cascade and calcium influx. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in testis and tumoral cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Brandenberger,R.,(2004)Nat.Biotechnol.22(6),707-716ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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