SLC2A8 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9NY64 |
Other Accession | NM_014580, NP_055395 |
Reactivity | Human, Rabbit |
Predicted | Human, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 51kDa |
Gene ID | 29988 |
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Alias Symbol | GLUT8, GLUTX1 |
Other Names | Solute carrier family 2, facilitated glucose transporter member 8, Glucose transporter type 8, GLUT-8, Glucose transporter type X1, SLC2A8, GLUT8, GLUTX1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC2A8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SLC2A8 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC2A8 (HGNC:13812) |
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Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (By similarity). Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1 (PubMed:27922102). Also able to mediate the transport of dehydroascorbate. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration {ECO:0000250|UniProtKB:Q9JJZ1} |
Tissue Location | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues |
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