SLC33A1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | O00400 |
Other Accession | NM_004733, NP_004724 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Guinea Pig, Dog |
Predicted | Mouse, Rabbit, Zebrafish, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 61kDa |
Gene ID | 9197 |
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Alias Symbol | ACATN, AT-1, AT1, SPG42, CCHLND |
Other Names | Acetyl-coenzyme A transporter 1, AT-1, Acetyl-CoA transporter 1, Solute carrier family 33 member 1, SLC33A1, ACATN, AT1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC33A1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SLC33A1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC33A1 (HGNC:95) |
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Synonyms | ACATN, AT1 |
Function | Acetyl-CoA transporter that mediates active acetyl-CoA import through the endoplasmic reticulum (ER) membrane into the ER lumen where specific ER-based acetyl-CoA:lysine acetyltransferases are responsible for the acetylation of ER-based protein substrates, such as BACE1 (PubMed:20826464, PubMed:24828632). Necessary for O-acetylation of gangliosides (PubMed:9096318). |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. With strongest signals in pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
References
Hirabayashi,Y.,(2004)PflugersArch.447(5),760-762ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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