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UBE2L3 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - UBE2L3 antibody - C-terminal region AI12207
    Human Intestine
    detail
  • WB - UBE2L3 antibody - C-terminal region AI12207

    WB Suggested Anti-UBE2L3 Antibody Titration: 1.25μg/ml
    Positive Control: Jurkat cell lysate
    There is BioGPS gene expression data showing that UBE2L3 is expressed in Jurkat
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P68036
Other Accession NM_004739, NP_003338
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 75kDa
Additional Information
Gene ID 7332
Alias Symbol E2-F1, L-UBC, UBCH7, UbcM4
Other Names Ubiquitin-conjugating enzyme E2 L3, 6.3.2.19, L-UBC, UbcH7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3, UBE2L3, UBCE7, UBCH7
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-UBE2L3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUBE2L3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2L3
Synonyms UBCE7, UBCH7
Function Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN, RNF31 and ARIH1, that function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
Cellular Location Nucleus. Cytoplasm
Tissue Location Ubiquitous, with highest expression in testis.
Research Areas
Citations (0)
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$ 339.00
Cat# AI12207
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