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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > UBE2D1 antibody - middle region
UBE2D1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P51668 |
| Other Accession | NM_001204880, NP_003329 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Mouse, Zebrafish, Pig, Chicken, Goat, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 16kDa |
| Gene ID | 7321 |
|---|---|
| Alias Symbol | E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A |
| Other Names | Ubiquitin-conjugating enzyme E2 D1, 6.3.2.19, Stimulator of Fe transport, SFT, UBC4/5 homolog, UbcH5, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2(17)KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1, UBE2D1, SFT, UBC5A, UBCH5, UBCH5A |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-UBE2D1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | UBE2D1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBE2D1 |
|---|---|
| Synonyms | SFT, UBC5A, UBCH5, UBCH5A |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Ubiquitous. Up-regulated in livers of iron- overloaded patients with hereditary hemochromatosis |
Research Areas
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Application Protocols
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$ 339.00
Cat# AI12203
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