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UBE2D1 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - UBE2D1 antibody - middle region AI12203

    WB Suggested Anti-UBE2D1 Antibody Titration: 1.25μg/ml
    Positive Control: Jurkat cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P51668
Other Accession NM_001204880, NP_003329
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Mouse, Zebrafish, Pig, Chicken, Goat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 16kDa
Additional Information
Gene ID 7321
Alias Symbol E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
Other Names Ubiquitin-conjugating enzyme E2 D1, 6.3.2.19, Stimulator of Fe transport, SFT, UBC4/5 homolog, UbcH5, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2(17)KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1, UBE2D1, SFT, UBC5A, UBCH5, UBCH5A
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-UBE2D1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUBE2D1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2D1
Synonyms SFT, UBC5A, UBCH5, UBCH5A
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148).
Cellular Location Cytoplasm.
Tissue Location Ubiquitous. Up-regulated in livers of iron- overloaded patients with hereditary hemochromatosis
Research Areas
Citations (0)
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$ 339.00
Cat# AI12203
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