CD40 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P25942 |
Other Accession | NM_001250, NP_001241 |
Reactivity | Human, Rabbit |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 30kDa |
Gene ID | 958 |
---|---|
Alias Symbol | Bp50, CDW40, MGC9013, TNFRSF5, p50 |
Other Names | Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40, CD40, TNFRSF5 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CD40 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CD40 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD40 |
---|---|
Synonyms | TNFRSF5 |
Function | Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). |
Cellular Location | [Isoform I]: Cell membrane; Single-pass type I membrane protein |
Tissue Location | B-cells and in primary carcinomas. |
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Provided below are standard protocols that you may find useful for product applications.
References
von (2006) Blood 107 (7), 2786-2789Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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