LBP antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | P18428 |
Other Accession | NM_004139, NP_004130 |
Reactivity | Human, Pig, Horse, Bovine |
Predicted | Human, Pig, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 51kDa |
Gene ID | 3929 |
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Alias Symbol | MGC22233, BPIFD2 |
Other Names | Lipopolysaccharide-binding protein, LBP, LBP |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LBP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | LBP antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LBP |
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Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:24120359, PubMed:7517398). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:24120359, PubMed:7517398). |
Cellular Location | Secreted. Cytoplasmic granule membrane {ECO:0000250|UniProtKB:P17213}. Note=Membrane- associated in polymorphonuclear Leukocytes (PMN) granules {ECO:0000250|UniProtKB:P17213} |
Tissue Location | Detected in blood serum (at protein level). |

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