PRPF6 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O94906 |
Other Accession | NM_012469, NP_036601 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog |
Predicted | Rabbit, Chicken, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 104kDa |
Gene ID | 24148 |
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Alias Symbol | ANT-1, TOM, ANT1, Prp6, hPrp6, U5-102K, C20orf14 |
Other Names | Pre-mRNA-processing factor 6, Androgen receptor N-terminal domain-transactivating protein 1, ANT-1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein, PRPF6, C20orf14 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-PRPF6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PRPF6 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRPF6 (HGNC:15860) |
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Synonyms | C20orf14 |
Function | Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:20118938, PubMed:21549338, PubMed:28781166). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. |
Cellular Location | Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles. |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
References
Fan,S., (2006) Biochem. Biophys. Res. Commun. 341 (1), 192-201Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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