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LSM6 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - LSM6 antibody - middle region AI11787

    WB Suggested Anti-LSM6 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: HCT15 cell lysate
    LSM6 is supported by BioGPS gene expression data to be expressed in HCT15
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P62312
Other Accession NM_007080, NP_009011
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Yeast, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 9kDa
Additional Information
Gene ID 11157
Alias Symbol YDR378°C
Other Names U6 snRNA-associated Sm-like protein LSm6, LSM6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-LSM6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLSM6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LSM6
Function Plays a role in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).
Cellular Location Cytoplasm. Nucleus
Research Areas
Citations (0)
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$ 389.00
Cat# AI11787
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