TROVE2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P10155 |
Other Accession | NM_001042369, NP_001035828 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog |
Predicted | Mouse, Pig, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 58kDa |
Gene ID | 6738 |
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Alias Symbol | RO60, SSA2, RORNP |
Other Names | 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2, TROVE2, RO60, SSA2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TROVE2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TROVE2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RO60 (HGNC:11313) |
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Function | RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853). Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance (By similarity). |
Cellular Location | Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
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Provided below are standard protocols that you may find useful for product applications.
References
Hennig,J., (2005) J. Biol. Chem. 280 (39), 33250-33261Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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