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TROVE2 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - TROVE2 antibody - N-terminal region AI11761
    Rabbit Anti-TROVE2 Antibody
    Paraffin Embedded Tissue: Human Kidney
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
    detail
  • WB - TROVE2 antibody - N-terminal region AI11761

    WB Suggested Anti-TROVE2 Antibody Titration: 2.5μg/ml
    Positive Control: HepG2 cell lysate
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P10155
Other Accession NM_001042369, NP_001035828
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Predicted Human, Rat, Pig, Chicken, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 58kDa
Additional Information
Gene ID 6738
Alias Symbol RO60, SSA2, RORNP
Other Names 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2, TROVE2, RO60, SSA2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-TROVE2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTROVE2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RO60 (HGNC:11313)
Function RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853). Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance (By similarity).
Cellular Location Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Research Areas
Citations (0)
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References

Hennig,J., (2005) J. Biol. Chem. 280 (39), 33250-33261Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 339.00
Cat# AI11761
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