EBF1 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
---|---|
Primary Accession | Q9UH73 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rabbit, Zebrafish, Pig, Chicken, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 64kDa |
Gene ID | 1879 |
---|---|
Alias Symbol | EBF, COE1, OLF1, O/E-1 |
Other Names | Transcription factor COE1, O/E-1, OE-1, Early B-cell factor, EBF1, COE1, EBF |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-EBF1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | EBF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EBF1 |
---|---|
Synonyms | COE1, EBF |
Function | Key pioneer transcription factor of B-cell specification and commitment (PubMed:27807034). Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B- cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity). |
Cellular Location | Nucleus. |

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