PATZ1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9HBE1 |
Other Accession | NM_014323, NP_055138 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rabbit, Pig, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 74kDa |
Gene ID | 23598 |
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Alias Symbol | MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23 |
Other Names | POZ-, AT hook-, and zinc finger-containing protein 1, BTB/POZ domain zinc finger transcription factor, Protein kinase A RI subunit alpha-associated protein, Zinc finger and BTB domain-containing protein 19, Zinc finger protein 278, Zinc finger sarcoma gene protein, PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PATZ1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PATZ1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PATZ1 |
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Synonyms | PATZ, RIAZ, ZBTB19, ZNF278, ZSG |
Function | Transcriptional regulator that plays a role in many biological processes such as embryogenesis, senescence, T-cell development or neurogenesis (PubMed:10713105, PubMed:25755280, PubMed:31875552). Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53 (PubMed:25755280). Part of the transcriptional network modulating regulatory T-cell development and controls the generation of the regulatory T-cell pool under homeostatic conditions (PubMed:31875552). |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
References
Fedele,M., (2008) J. Pathol. 215 (1), 39-47 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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