PPARD antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q03181 |
Other Accession | NM_001039694, NP_001034783 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog |
Predicted | Mouse, Rat, Pig, Chicken, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 49kDa |
Gene ID | 5467 |
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Alias Symbol | FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB |
Other Names | Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta, PPARD, NR1C2, PPARB |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PPARD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PPARD antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPARD (HGNC:9235) |
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Synonyms | NR1C2, PPARB |
Function | Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed:35675826). Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma- linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous with maximal levels in placenta and skeletal muscle |
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