PRDM15 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P57071 |
Other Accession | NM_144771, NP_658984 |
Reactivity | Human, Mouse, Rat, Pig, Bovine, Dog |
Predicted | Human, Mouse, Rat, Pig, Chicken, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39kDa |
Gene ID | 63977 |
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Alias Symbol | C21orf83, PFM15, ZNF298 |
Other Names | PR domain zinc finger protein 15, 2.1.1.-, PR domain-containing protein 15, Zinc finger protein 298, PRDM15, C21orf83, ZNF298 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PRDM15 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PRDM15 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRDM15 (HGNC:13999) |
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Function | Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development (By similarity). Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming (PubMed:28740264). |
Cellular Location | Nucleus. |
Tissue Location | Detected in all tissues examined. |
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