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ASGR2 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - ASGR2 antibody - N-terminal region AI10664
    Human Spleen
    detail
  • WB - ASGR2 antibody - N-terminal region AI10664

    WB Suggested Anti-ASGR2 Antibody Titration: 4.0μg/ml
    Positive Control: HepG2 cell lysate
    ASGR2 is supported by BioGPS gene expression data to be expressed in HepG2
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P07307
Other Accession NM_001181, NP_001172
Reactivity Human, Pig
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Additional Information
Gene ID 433
Alias Symbol HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2
Other Names Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, C-type lectin domain family 4 member H2, Hepatic lectin H2, HL-2, ASGR2, CLEC4H2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-ASGR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsASGR2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASGR2
Synonyms CLEC4H2
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N- acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Cellular Location Membrane; Single-pass type II membrane protein.
Tissue Location Expressed exclusively in hepatic parenchymal cells.
Research Areas
Citations (0)
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References

Yik,J.H.,et al., (2002) J.Biol.Chem.277(43),40844-40852Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 339.00
Cat# AI10664
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