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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PPP1R13L antibody - middle region   

PPP1R13L antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - PPP1R13L antibody - middle region AI10420
    WB Suggested Anti-PPP1R13L Antibody Titration: .2-1 μg/ml
    Positive Control: Transfected 293T
    detail
  • IHC - PPP1R13L antibody - middle region AI10420
    Sample Type :
    Human lung adenocarcinoma cell line A549

    Primary Antibody Dilution :

    1:1

    Secondary Antibody :

    Goat anti-rabbit AlexaFluor 488
    Secondary Antibody Dilution :
    1:4
    Color/Signal Descriptions :
    PPP1R13L: Green DAPI:Blue

    Gene Name :

    PPP1R13L
    Submitted by :
    Dr. Crissy Dudgeon, Ph.D., CINJ
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q8WUF5
Other Accession NM_006663, NP_006654
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Additional Information
Gene ID 10848
Alias Symbol IASPP, NKIP1, RAI, iASPP gene, RAI4
Other Names RelA-associated inhibitor, Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein, PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PPP1R13L antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPPP1R13L antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R13L
Synonyms IASPP, NKIP1, PPP1R13BL, RAI
Function Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540). Is involved in NF-kappa-B dependent negative regulation of inflammatory response (PubMed:28069640).
Cellular Location Cytoplasm. Nucleus Note=Predominantly cytoplasmic but also nuclear
Tissue Location Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.
Research Areas
Citations (0)
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References

Tomoda,K., (2008) Cancer Sci. 99 (3), 615-622 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 389.00
Cat# AI10420
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