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MEOX1 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - MEOX1 antibody - N-terminal region AI10403
    WB Suggested Anti-MEOX1 Antibody Titration: .2-1 μg/ml
    Positive Control: Jurkat cell lysate
    detail
  • IHC - MEOX1 antibody - N-terminal region AI10403
    Human Liver
    detail
  • IHC - MEOX1 antibody - N-terminal region AI10403
    Human Stomach
    detail
  • IHC - MEOX1 antibody - N-terminal region AI10403
    Rabbit Anti-MEOX1 Antibody

    Catalog Number:
    AI10403

    Paraffin Embedded Tissue:
    Human cardiac cell

    Cellular Data:
    Epithelial cells of renal tubule

    Antibody Concentration:
    4.-8. μg/ml

    Magnification:
    4X
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P50221
Other Accession NM_004527, NP_004518
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Pig, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 4222
Alias Symbol MOX1
Other Names Homeobox protein MOX-1, Mesenchyme homeobox 1, MEOX1, MOX1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MEOX1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMEOX1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEOX1
Synonyms MOX1
Function Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Cellular Location Nucleus {ECO:0000250|UniProtKB:P32442}. Cytoplasm {ECO:0000250|UniProtKB:P32442}. Note=Localizes predominantly in the nucleus. {ECO:0000250|UniProtKB:P32442}
Research Areas
Citations (0)
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References

Jones,K.A., et al., (1994) Hum.Mol.Genet.3(11),1927-1934Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 389.00
Cat# AI10403
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Availability: 2-3 days
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