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GATA3 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - GATA3 antibody - C-terminal region AI10379
    WB Suggested Anti-GATA3 Antibody Titration: .2-1 μg/ml
    Positive Control: Jurkat cell lysate

    There is BioGPS gene expression data showing that GATA3 is expressed in Jurkat

    detail
  • IHC - GATA3 antibody - C-terminal region AI10379
    Rabbit Anti-GATA3 Antibody
    Catalog Number: AI10379
    Paraffin Embedded Tissue: Human Liver
    Cellular Data: Hepatocyte
    Antibody Concentration: 4.-8. μg/ml
    Magnification: 4X
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF
Primary Accession P23771
Other Accession NM_002051, NP_002042
Reactivity Human, Mouse, Rat, Pig, Sheep, Bovine, Horse, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Sheep, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 2625
Alias Symbol HDR, HDRS
Other Names Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GATA3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGATA3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA3
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
Cellular Location Nucleus.
Tissue Location T-cells and endothelial cells.
Research Areas
Citations (0)
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References

Kaminuma,O., et al., (2004) FEBS Lett.570(1-3),63-68Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 389.00
Cat# AI10379
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