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GATA3 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF |
|---|---|
| Primary Accession | P23771 |
| Other Accession | NM_002051, NP_002042 |
| Reactivity | Human, Mouse, Rat, Pig, Sheep, Bovine, Horse, Dog |
| Predicted | Human, Mouse, Rat, Pig, Chicken, Sheep, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48kDa |
| Gene ID | 2625 |
|---|---|
| Alias Symbol | HDR, HDRS |
| Other Names | Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GATA3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GATA3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GATA3 |
|---|---|
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages. |
| Cellular Location | Nucleus. |
| Tissue Location | T-cells and endothelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Kaminuma,O., et al., (2004) FEBS Lett.570(1-3),63-68Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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