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MINA Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8IUF8 |
| Other Accession | Q8IUF8-3, NP_694822, NM_153182 |
| Reactivity | Human, Rat, Rabbit, Pig, Dog |
| Predicted | Human, Rat, Rabbit, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23 kDa |
| Gene ID | 84864 |
|---|---|
| Alias Symbol | MDIG, MINA53, NO52 |
| Other Names | Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, 11411-, 60S ribosomal protein L27a histidine hydroxylase, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, MINA (HGNC:19441) |
| Target/Specificity | MINA is a c-Myc target gene that may play a role in cell proliferation or regulation of cell growth. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul, l of distilled water. Final Anti-MINA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | MINA Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RIOX2 (HGNC:19441) |
|---|---|
| Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| Cellular Location | Nucleus. Nucleus, nucleolus |
| Tissue Location | Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against MINA. It was validated on Western Blot by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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If you have any additional inquiries please email technical services at tech@abcepta.com.
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