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> home > Products > Primary Antibodies > Signal Transduction > Anti-Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Antibody
Anti-Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Antibody
Mouse Monoclonal Antibody
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- BACKGROUND
Application 
| WB, IHC-P, IF, FC |
|---|---|
| Primary Accession | P01011 |
| Other Accession | 534293, 710488 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgG1 |
| Clone Names | AACT/1451 |
| Calculated MW | 47651 Da |
| Gene ID | 12 |
|---|---|
| Other Names | SERPINA3; AACT; ACT; Alpha-1-antichymotrypsin; Antichymotrypsin; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; Serine (or cysteine) proteinase inhibitor clade A member 3; Serine proteinase inhibitor clade A member 3; Serpin A3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 |
| Application Note | Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1ug/ml); western Blotting (0.5-1.0ug/ml);,Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined. |
| Format | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | Anti-Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERPINA3 |
|---|---|
| Synonyms | AACT |
| Function | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. |
Research Areas
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$ 239.00
Cat# AH13135-20
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