Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Napsin A (Lung Adenocarcinoma Marker) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone NAPSA/1238 ]
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, FC |
|---|---|
| Primary Accession | O96009 |
| Other Accession | 9476, 512843 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgG, kappa |
| Clone Names | NAPSA/1238 |
| Calculated MW | 37kDa |
| Gene ID | 9476 |
|---|---|
| Other Names | Napsin-A, 3.4.23.-, Aspartyl protease 4, ASP4, Asp 4, Napsin-1, TA01/TA02, NAPSA, NAP1, NAPA |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | Napsin A (Lung Adenocarcinoma Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAPSA |
|---|---|
| Synonyms | NAP1, NAPA |
| Function | May be involved in processing of pneumocyte surfactant precursors. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.ĀThere are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
References
Bishop, JA et. al. Hum Pathol 41: 20-25 | Ordonez, NG 2012 Adv Anat Pathol 19: 66-73 | Ye, J et. al. Appl Immunhistochem Mol Morphol 19: 313-31
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
