GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor) Antibody - With BSA and Azide
Rat Monoclonal Antibody [Clone SPM469 ]
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-F, IF, FC, IP |
---|---|
Primary Accession | P04141 |
Other Accession | 1437, 1349 |
Reactivity | Human, Rhesus, Cynomolgus |
Host | Rat |
Clonality | Monoclonal |
Isotype | Rat / IgG2a, kappa |
Clone Names | SPM469 |
Calculated MW | 22kDa |
Gene ID | 1437 |
---|---|
Other Names | Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF |
Format | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
Precautions | GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CSF2 |
---|---|
Synonyms | GMCSF |
Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
Cellular Location | Secreted |
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Provided below are standard protocols that you may find useful for product applications.
Background
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
References
Abrams J, et al. 1992. Immunol. Rev. 127:5. | Abrams J, et al. 1994. Eosinophils in Allergy and Inflammation. Marcel Dekker New York. p.133. | Bacchetta R, et al. 1990. J. Immunol. 144:902. | Kita H, et al. 1991. J. Exp. Med. 174:745. | Andersson U, et al. 1999. Detection and quantification of gene expression. New York:Springer-Verlag. | Andersson J, et al. 1994. Immunology 83:16
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