Goat anti-OCIL Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IF, FC, Pep-ELISA |
---|---|
Primary Accession | Q9UHP7 |
Other Accession | NP_037401.1, NP_001004419.1, NP_001184246.1 |
Reactivity | Human, Dog, Bovine |
Host | Goat |
Clonality | Polyclonal |
Clone Names | CLEC2D |
Calculated MW | 21849 Da |
Gene ID | 29121 |
---|---|
Other Names | CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin related f; C-type lectin superfamily 2, member D; lectin-like NK cell receptor; lectin-like transcript 1; osteoclast inhibitory lectin |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | This antibody is expected to recognize all isoforms (NP_037401.1; NP_001004419.1; NP_001184246.1). |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-OCIL Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CLEC2D |
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Synonyms | CLAX, LLT1, OCIL |
Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:16339513, PubMed:20843815). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656). |
Cellular Location | Cell membrane; Single-pass type II membrane protein [Isoform 4]: Endoplasmic reticulum |
Tissue Location | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. |

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