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Goat anti-SOX10 (aa204-217) Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, Pep-ELISA
Primary Accession P56693
Other Accession NP_008872.1
Reactivity Human, Mouse, Rat, Pig, Dog, Bovine
Host Goat
Clonality Polyclonal
Clone Names SOX10
Calculated MW 49911 Da
Additional Information
Gene ID 6663
Other Names SOX10; SRY (sex determining region Y)-box 10; DOM; MGC15649; PCWH; WS2E; WS4; WS4C; OTTHUMP00000195094; OTTHUMP00000195097; SRY-related HMG-box gene 10; dominant megacolon, mouse, human homolog of; transcription factor SOX-10
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-SOX10 (aa204-217) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX10
Function Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Cellular Location Cytoplasm. Nucleus. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888}
Tissue Location Expressed in fetal brain and in adult brain, heart, small intestine and colon
Research Areas
Citations (0)
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$ 392.00
Cat# AF4509a
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