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Goat anti-ERCC1 Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IF, Pep-ELISA
Primary Accession P07992
Other Accession NP_973730.1, NP_001974.1, NP_001159521.1
Reactivity Human, Mouse, Rat, Dog, Bovine
Host Goat
Clonality Polyclonal
Clone Names ERCC1
Calculated MW 32562 Da
Additional Information
Gene ID 2067
Other Names ERCC1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); COFS4; UV20; excision repair cross-complementing 1; excision repair protein
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-ERCC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERCC1
Function [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Cellular Location [Isoform 1]: Nucleus [Isoform 3]: Nucleus
Research Areas
Citations (0)
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$ 341.00
Cat# AF4504a
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Availability: 7-10 days
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