Goat anti-ERCC1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IF, Pep-ELISA |
---|---|
Primary Accession | P07992 |
Other Accession | NP_973730.1, NP_001974.1, NP_001159521.1 |
Reactivity | Human, Mouse, Rat, Dog, Bovine |
Host | Goat |
Clonality | Polyclonal |
Clone Names | ERCC1 |
Calculated MW | 32562 Da |
Gene ID | 2067 |
---|---|
Other Names | ERCC1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); COFS4; UV20; excision repair cross-complementing 1; excision repair protein |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-ERCC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ERCC1 |
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Function | [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. |
Cellular Location | [Isoform 1]: Nucleus [Isoform 3]: Nucleus |
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