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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-EWS / EWSR1, Biotinylated Antibody
Goat anti-EWS / EWSR1, Biotinylated Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | Q01844 |
| Other Accession | NP_053733.2, NP_005234.1, NP_001156757.1, NP_001156758.1, NP_001156759.1 |
| Reactivity | Human, Mouse, Rat, Pig, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | EWSR1 |
| Calculated MW | 68478 Da |
| Gene ID | 2130 |
|---|---|
| Other Names | EWSR1; EWS; Ewing sarcoma breakpoint region 1; EWS/FLI fusion protein; EWSR1/ZNF384 fusion protein; Ewings sarcoma EWS-Fli1 (type 1) oncogene; bK984G1.4 (Ewing sarcoma breakpoint region 1 protein); extraskeletal myxoid chondrosarcoma EWS/TEC/CHN fusion pr |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize all five reported isoforms (NP_053733.2; NP_005234.1; NP_001156757.1; NP_001156758.1; NP_001156759.1). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-EWS / EWSR1, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EWSR1 |
|---|---|
| Synonyms | EWS |
| Function | Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Cellular Location | Nucleus. Cytoplasm. Cell membrane. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation |
| Tissue Location | Ubiquitous. |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4479a
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