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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-SEPT6, Biotinylated Antibody
Goat anti-SEPT6, Biotinylated Antibody
Peptide-affinity purified goat antibody
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Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | Q14141 |
| Other Accession | NP_665798.1, NP_055944.2, NP_665801.1 |
| Reactivity | Human, Dog, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | SEPTIN6 |
| Calculated MW | 49717 Da |
| Gene ID | 23157 |
|---|---|
| Other Names | SEPT6; septin 6; KIAA0128; MGC16619; MGC20339; SEP2; SEPT2; septin 2 |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-SEPT6, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SEPTIN6 (HGNC:15848) |
|---|---|
| Synonyms | KIAA0128, SEP2, SEPT6 |
| Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle Chromosome, centromere, kinetochore Cleavage furrow. Midbody. Cell projection, cilium, flagellum. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. Found in the sperm annulus (PubMed:25588830). |
| Tissue Location | Widely expressed.. |
Research Areas
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Application Protocols
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$ 423.00
Cat# AF4478a
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