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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-GOT1 (aa 157-167), Biotinylated Antibody
Goat anti-GOT1 (aa 157-167), Biotinylated Antibody
Peptide-affinity purified goat antibody
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Application 
| WB, IHC, Pep-ELISA |
|---|---|
| Primary Accession | P17174 |
| Other Accession | NP_002070.1 |
| Reactivity | Human, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | GOT1 |
| Calculated MW | 46248 Da |
| Gene ID | 2805 |
|---|---|
| Other Names | GOT1; glutamic-oxaloacetic transaminase 1; AST1; ASTQTL1; GIG18; cAspAT; cCAT; aspartate aminotransferase 1; aspartate transaminase 1; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; glutamate oxaloacetate transaminase 1; gluta |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-GOT1 (aa 157-167), Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GOT1 (HGNC:4432) |
|---|---|
| Function | Biosynthesis of L-glutamate from L-aspartate or L-cysteine (PubMed:21900944). Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. In addition, catalyzes (2S)-2- aminobutanoate, a by-product in the cysteine biosynthesis pathway (PubMed:27827456). |
| Cellular Location | Cytoplasm. |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4432a
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