Goat anti-ACAT1 (aa257-269), Biotinylated Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, Pep-ELISA |
---|---|
Primary Accession | P24752 |
Other Accession | NP_000010.1 |
Reactivity | Human, Mouse, Rat, Bovine |
Host | Goat |
Clonality | Polyclonal |
Clone Names | ACAT1 |
Calculated MW | 45200 Da |
Gene ID | 38 |
---|---|
Other Names | ACAT1; acetyl-CoA acetyltransferase 1; ACAT; MAT; T2; THIL; acetoacetyl Coenzyme A thiolase; acetoacetyl-CoA thiolase; acetyl-Coenzyme A acetyltransferase 1; mitochondrial acetoacetyl-CoA thiolase |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-ACAT1 (aa257-269), Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACAT1 |
---|---|
Synonyms | ACAT, MAT |
Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (PubMed:1715688, PubMed:7728148, PubMed:9744475). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (PubMed:1715688, PubMed:7728148, PubMed:9744475). The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA (PubMed:17371050). Thereby, it plays a major role in ketone body metabolism (PubMed:1715688, PubMed:17371050, PubMed:7728148, PubMed:9744475). |
Cellular Location | Mitochondrion. |
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