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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-CIRBP (aa 161-172), Biotinylated Antibody
Goat anti-CIRBP (aa 161-172), Biotinylated Antibody
Peptide-affinity purified goat antibody
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Application 
| WB, IHC, Pep-ELISA |
|---|---|
| Primary Accession | Q14011 |
| Other Accession | NP_001271.1 |
| Reactivity | Human, Mouse, Rat, Dog, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | CIRBP |
| Calculated MW | 18648 Da |
| Gene ID | 1153 |
|---|---|
| Other Names | CIRBP; cold inducible RNA binding protein; CIRP; A18 hnRNP; cold inducible RNA-binding protein; glycine-rich RNA binding protein |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize reported isoform 1 (NP_001271.1) only. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-CIRBP (aa 161-172), Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CIRBP |
|---|---|
| Synonyms | A18HNRNP, CIRP |
| Function | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'- UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
| Cellular Location | Nucleus, nucleoplasm. Cytoplasm Note=Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins (By similarity). |
| Tissue Location | Ubiquitous. |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4392a
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