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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-ITGA3 (isoform a) Antibody
Goat anti-ITGA3 (isoform a) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | P26006 |
| Other Accession | NP_002195.1 |
| Reactivity | Human, Mouse, Pig, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | ITGA3 |
| Calculated MW | 116612 Da |
| Gene ID | 3675 |
|---|---|
| Other Names | ITGA3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); CD49C; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a; CD49 antigen-like family member C; FRP-2; VLA-3 subunit alpha; antigen identified by monoclonal antibody J143; galactoprot |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize reported isoform a (NP_002195.1). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-ITGA3 (isoform a) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ITGA3 |
|---|---|
| Synonyms | MSK18 |
| Function | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha- 3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid- anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner. |
| Tissue Location | Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF4390a
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