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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-HSULF-1 / sulfatase 1 Antibody
Goat anti-HSULF-1 / sulfatase 1 Antibody
Peptide-affinity purified goat antibody
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- CITATIONS
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- BACKGROUND
Application 
| Pep-ELISA |
|---|---|
| Primary Accession | Q8IWU6 |
| Other Accession | NP_055985.2 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | SULF1 |
| Calculated MW | 101027 Da |
| Gene ID | 23213 |
|---|---|
| Other Names | SULF1; sulfatase 1; HSULF-1; SULF-1; extracellular sulfatase Sulf-1; sulfatase FP |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Reported variants NP_055985.2; NP_001121676.1; NP_001121677.1; NP_001121678.1 represent identical protein |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-HSULF-1 / sulfatase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SULF1 |
|---|---|
| Synonyms | KIAA1077 |
| Function | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:12686563). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (PubMed:12368295, PubMed:12686563). Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation (PubMed:12686563). |
| Cellular Location | Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VI60}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q8VI60}. Cell surface |
| Tissue Location | Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down- regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines |
Research Areas
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$ 216.00
Cat# AF4377a
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