Goat anti-periostin (aa112-125) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, Pep-ELISA |
---|---|
Primary Accession | Q15063 |
Other Accession | NP_006466.2, NP_001129406.1, NP_001129407.1, NP_001129408.1 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Clone Names | POSTN |
Calculated MW | 93314 Da |
Gene ID | 10631 |
---|---|
Other Names | POSTN; periostin, osteoblast specific factor; MGC119510; MGC119511; OSF-2; OSF2; PDLPOSTN; PN; RP11-412K4.1; periostin; OTTHUMP00000018268; OTTHUMP00000018269; OTTHUMP00000018270; OTTHUMP00000018271; osteoblast specific factor 2 (fasciclin I-like); osteob |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | This antibody is expected to recognize all reported isoforms (NP_006466.2; NP_001129406.1; NP_001129407.1; NP_001129408.1). |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-periostin (aa112-125) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | POSTN |
---|---|
Synonyms | OSF2 |
Function | Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). |
Cellular Location | Golgi apparatus {ECO:0000250|UniProtKB:Q62009}. Secreted Secreted, extracellular space, extracellular matrix Note=Colocalizes with BMP1 in the Golgi {ECO:0000250|UniProtKB:Q62009} |
Tissue Location | Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Expressed in the kidney (PubMed:21763681). Expressed in the lung (PubMed:22079858). Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor Overexpressed in breast cancers. |

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