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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody   

Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, Pep-ELISA
Primary Accession P55008
Other Accession NP_116573.1, NP_004838.1, NP_001614.3
Reactivity Human, Mouse, Rat, Pig
Host Goat
Clonality Polyclonal
Clone Names AIF1
Calculated MW 16703 Da
Additional Information
Gene ID 199
Other Names AIF1; allograft inflammatory factor 1; AIF-1; IBA1; IRT-1; IRT1; allograft inflammatory factor-1 splice variant Hara-1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; protein G1
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen This antibody is expected to recognize isoform 1 (NP_116573.1) and isoform 3 (NP_001614.3).
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AIF1
Synonyms G1, IBA1
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Cellular Location Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O70200}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:O70200}; Peripheral membrane protein {ECO:0000250|UniProtKB:O70200}; Cytoplasmic side {ECO:0000250|UniProtKB:O70200}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:O70200}. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis {ECO:0000250|UniProtKB:O70200}
Tissue Location Detected in T-lymphocytes and peripheral blood mononuclear cells.
Research Areas
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$ 341.00
Cat# AF4347a
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