Goat Anti-IRF4 (aa393-407) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, Pep-ELISA |
---|---|
Primary Accession | Q15306 |
Other Accession | NP_002451.2, NP_001182215.1 |
Reactivity | Human, Rat |
Host | Goat |
Clonality | Polyclonal |
Clone Names | IRF4 |
Calculated MW | 51772 Da |
Gene ID | 3662 |
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Other Names | interferon regulatory factor 4, LSIRF, multiple myeloma oncogene 1, MUM1, IRF4 |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Immunogen | Peptide with sequence C-DPQRQRKLITAHVEP, from the internal region (near C Terminus) of the protein sequence according to NP_002451.2; NP_001182215.1. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-IRF4 (aa393-407) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IRF4 |
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Synonyms | MUM1 |
Function | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA- 3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Lymphoid cells. |
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