Goat Anti-Endophilin-A1 / SH3GL2 Antibody (internal region), Biotinylated
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q99962 |
Other Accession | NP_003017.1, 6456 |
Reactivity | Human |
Predicted | Human, Pig |
Host | Goat |
Isotype | IgG |
Calculated MW | 39962 Da |
Gene ID | 6456 |
---|---|
Other Names | Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-Endophilin-A1 / SH3GL2 Antibody (internal region), Biotinylated is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SH3GL2 |
---|---|
Synonyms | CNSA2, SH3D2A |
Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O35179}. Membrane {ECO:0000250|UniProtKB:O35179}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35179}. Early endosome {ECO:0000250|UniProtKB:Q62420}. Presynapse {ECO:0000250|UniProtKB:O35179} |
Tissue Location | Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum |
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