Goat Anti-ALDH3A2 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, E |
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Primary Accession | P51648 |
Other Accession | NP_001026976.1, NP_000373.1 |
Reactivity | Human |
Predicted | Human, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 |
Calculated MW | 54848 Da |
Gene ID | 224 |
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Other Names | ALDH3A2; aldehyde dehydrogenase 3 family, member A2; ALDH10; DKFZp686E23276; FALDH; FLJ20851; SLS; OTTHUMP00000065801; aldehyde dehydrogenase 10; aldehyde dehydrogenase 3A2; fatty aldehyde dehydrogenase |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | Peptide with sequence C-SLKREGANKLRYPP, from the internal region of the protein sequence according to NP_001026976.1; NP_000373.1. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-ALDH3A2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDH3A2 |
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Function | Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:18035827, PubMed:18182499, PubMed:22633490, PubMed:25047030, PubMed:9133646, PubMed:9662422). Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (PubMed:22633490). |
Cellular Location | Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side {ECO:0000250|UniProtKB:P30839} |
Tissue Location | Detected in liver (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
Abnormal fatty alcohol metabolism in cultured keratinocytes from patients with Sjögren-Larsson syndrome. Rizzo WB, Craft DA, Somer T, Carney G, Trafrova J, Simon M, Journal of lipid research 2008 Feb 49 (2): 410-9.
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