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Goat Anti-GNL3 Antibody (internal region)

Purified Goat Polyclonal Antibody

     
  • WB - Goat Anti-GNL3 Antibody (internal region) AF4185a
    AF4185a (0.03 µg/ml) staining of K562 nuclear lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BVP2
Other Accession NP_055181.3, NP_996561.1
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 61993 Da
Additional Information
Gene ID 26354
Other Names GNL3; guanine nucleotide binding protein-like 3 (nucleolar); C77032; E2IG3; NNP47; NS; E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide-binding protein-like 3; novel nucleolar protein 47; nucleolar GTP-binding protein 3; nucleostemin
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-TENKAKSGKQNS, from the internal region of the protein sequence according to NP_055181.3; NP_996561.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-GNL3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNL3
Synonyms E2IG3, NS
Function May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}
Tissue Location Increased levels in lung tissue in cancer patients.
Research Areas
Citations (0)
citation

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References

Nucleostemin affects the proliferation but not differentiation of oral squamous cell carcinoma cells. Yoshida R, Fujimoto T, Kudoh S, Nagata M, Nakayama H, Shinohara M, Ito T. Cancer science 2011 Jul 102 (7): 1418-23.

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$ 341.00
Cat# AF4185a
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Availability: 7-10 days
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