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Goat Anti-GNL3 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BVP2 |
| Other Accession | NP_055181.3, NP_996561.1 |
| Reactivity | Human |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 61993 Da |
| Gene ID | 26354 |
|---|---|
| Other Names | GNL3; guanine nucleotide binding protein-like 3 (nucleolar); C77032; E2IG3; NNP47; NS; E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide-binding protein-like 3; novel nucleolar protein 47; nucleolar GTP-binding protein 3; nucleostemin |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-TENKAKSGKQNS, from the internal region of the protein sequence according to NP_055181.3; NP_996561.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-GNL3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GNL3 |
|---|---|
| Synonyms | E2IG3, NS |
| Function | May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9} |
| Tissue Location | Increased levels in lung tissue in cancer patients. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Nucleostemin affects the proliferation but not differentiation of oral squamous cell carcinoma cells. Yoshida R, Fujimoto T, Kudoh S, Nagata M, Nakayama H, Shinohara M, Ito T. Cancer science 2011 Jul 102 (7): 1418-23.
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