LDHA Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P00338 |
Other Accession | NP_005557.1, NP_001128711.1, NP_001158886.1, 3939 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 36689 Da |
Gene ID | 3939 |
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Other Names | L-lactate dehydrogenase A chain, LDH-A, 1.1.1.27, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LDHA Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LDHA (HGNC:6535) |
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Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
Cellular Location | Cytoplasm. |
Tissue Location | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoform 1, 2 and 3 (NP_005557.1; NP_001128711.1; NP_001158886.1).
References
Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4. Zhang Y, Zhang X, Wang X, Gan L, Yu G, Chen Y, Liu K, Li P, Pan J, Wang J, Qin S. Cancer letters 2012 Aug 321 (1): 45-54. PMID: 22429998
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