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LDHA Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - LDHA Antibody (C-Term) AF4086a
    AF4086a (0.3 µg/ml) staining of Heart (A), Skeletal Muscle (B) and Kidney (C) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P00338
Other Accession NP_005557.1, NP_001128711.1, NP_001158886.1, 3939
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 36689 Da
Additional Information
Gene ID 3939
Other Names L-lactate dehydrogenase A chain, LDH-A, 1.1.1.27, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLDHA Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LDHA (HGNC:6535)
Function Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
Cellular Location Cytoplasm.
Tissue Location Predominantly expressed in anaerobic tissues such as skeletal muscle and liver.
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize isoform 1, 2 and 3 (NP_005557.1; NP_001128711.1; NP_001158886.1).

References

Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4. Zhang Y, Zhang X, Wang X, Gan L, Yu G, Chen Y, Liu K, Li P, Pan J, Wang J, Qin S. Cancer letters 2012 Aug 321 (1): 45-54. PMID: 22429998

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$ 341.00
Cat# AF4086a
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Availability: 7-10 days
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