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ABHD14B (aa188-200) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96IU4 |
| Other Accession | NP_116139.1, 84836, 76491 (mouse), 300983 (rat) |
| Reactivity | Human, Mouse, Rat |
| Predicted | Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 22346 Da |
| Gene ID | 84836 |
|---|---|
| Other Names | Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B, 3.-.-.-, CCG1-interacting factor B, ABHD14B, CIB |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ABHD14B (aa188-200) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ABHD14B {ECO:0000303|PubMed:31478652, ECO:0000312|HGNC:HGNC:28235} |
|---|---|
| Function | Acts as an atypical protein-lysine deacetylase in vitro (PubMed:31478652). Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein- lysine residues (PubMed:31478652). Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p- nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate (PubMed:14672934, PubMed:31478652). May activate transcription (PubMed:14672934). |
| Cellular Location | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic |
| Tissue Location | Ubiquitous (PubMed:14672934). Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney (PubMed:14672934). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_116139.1, NP_001139786.1. This antibody is expected to NOT cross-react with ABHD14A.
References
Purification, crystallization and preliminary X-ray crystallographic analysis of human CCG1-interacting factor B. Padmanabhan B, Kuzuhara T, Mizuno H, Horikoshi M. Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1479-81. PMID: 11053859
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